CLINICAL AND MORPHOLOGICAL ASPECTS OF THE EFFECTS OF HYPERBARIC OXYGEN THERAPY ON THE PROCESS OF ACUTE PYELONEPHRITIS

Shormanov Igor Sergeevich, Doctor of medical sciences, associate professor, head of sub-department of urology with nephrology, Yaroslavl State Medical Academy, i_s_shormanov@rambler.ru
Sokolova Khristina Alexandrovna, Candidate of medical sciences, assistant, sub-department of urology with nephrology, Yaroslavl State Medical Academy, manoylov@yandex.ru
Chirkov Alexander Nikolaevich, Candidate of medical sciences, associate professor, sub-department of urology with nephrology, Yaroslavl State Medical Academy, manoylov@yandex.ru
Ryzhkov Aleksey Igorevich, Postgraduate student, Yaroslavl State Medical Academy, 1129682@gmail.com

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The study is devoted to evaluating effectiveness of HBO in treatment of patients with acute pyelonephritis. Hyperbaric oxygen therapy was used in a complex of conservative treatment, as well as in the postoperative period. The course of HBO consisted of 8–10 sessions in the chamber at a pressure of 2.0-2.4 atm, 60 minutes. The positive effect of HBO consists in a decrease of SIRS and MOF frequency, an increase in glomerular filtration rate and improvement of renal hemodynamics. The use of hyperbaric oxygenation is accompanied by a tendency to restore the immune status. In experiments on white laboratory rats with a model of acute pyelonephritis demonstrated that HBO helps reduce inflammation in the renal tissue.

acute pyelonephritis, hyperbaric oxygen.